Les uses a 6-string but it's possible with a 4.

Main Riff
G|-----------------|
D|-----------------|
A|-7-4-----------4-|
E|-----6-3-0-3-6---|

Improv
G|----------12-----|
D|----------12-----|
A|-----------------|
E|-----------------|

G|-----12-15-14-11-|
D|-----12-15-15-11-|
A|-----------------|
E|-----------------|

Good one from the Holy Mackerel.