This is a very easy yet beautiful song to play on the guitar. 

This acoustic version features just voice and guitar.
Check it out here, acoustic performance by moby:
http://www.youtube.com/watch?v=k9yiHVji_lg

Chords Needed: C, Em, Am.

Tabbed by David Johen according to the acoustic video. Enjoy.
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(finger picking:)

      C
Don’t speak to me this way

      Em
Don’t ever let me say

      C
Don’t leave me again

      Em               Am
Don’t leave me again

                        C
Oh, you never felt this loss before

                 Em
And the world is closing doors

               Em              Am
I never wanted anything more

                        C
Oh, you never felt this loss before

                 Em
And the world is closing doors

               Em
I never wanted anything more

      C
Don’t touch me this way

      Em
Don’t leave me this way

      C
Don’t hurt me again

      Em
Don’t hurt me again

      C
Don't hurt me this way

      Em
Don’t touch me this way

      C
Don’t hurt me again

      Em (start strumming.....)   Asus2/Am     [Asus2: x02200]
Don’t hurt me again


(Strumming chords:)

                       C
Oh You never felt this loss before

                 Em
And the world is closing doors

               Em              Am     
I never wanted anything more

                       C
Oh You never felt this loss before

                 Em
And the world is closing doors

               Em              
I never wanted anything more


(Strumming slowly:)

C                             Em               C
   Don’t let me make the same mistake again

                                   Em             C
Please, don’t let me make the same mistake again

                           Em             C
Don’t let me make the same mistake again

                                   Em              Am
Please, don’t let me make the same mistake again

(Hard again:)
                       C
Oh you never felt this loss before

                 Em
And the world is closing doors

               Em             Am
I never wanted anything more

                       C
Oh you never felt this loss before

                 Em
And the world is closing doors

               Em             C
I never wanted anything more

(Harder:)
                           Em             C
Don’t let me make the same mistake again

                           Em             C
Don’t let me make the same mistake again

                                   Em             C
Please, Don’t let me make the same mistake again

(Slow Ending)              Em
Don’t let me make the same mistake again...