This is a great new song from Zakk.  Definitely one of his best.  I'm not 100% sure 
the solo because Zakk is a bit...um, crazy.  But awesome, nonetheless, so here goes.  
two guitars in the song.  One, obviously, is electric.  The other is an acoustic 12-string.

House of Doom
As performed on "Hangover Music Vol. 6"
Lyrics and music written by Zakk Wylde

Standard Eb tuning

h          hammer on
p          pull off
b          bend
r          return
~          vibrating
x          muffled strings
Zakk       Electric (Guitar 1)
Bkgrnd.    Acoustic (Guitar 2)

Intro pt. 1, Zakk (w/ clean tone, let chords ring)
eb[-2-----------------------2-----------------|
Bb[-2-----------------------2-----------------|
Gb[-4-----------------------4-----------------|
Db[-4-----------------------4-----------------|
Ab[-2-----------------------2-----------------|
Eb[-------------------------------------------|

Intro pt. 2, Zakk (w/ distortion, let chords ring)
eb[-----------------------------------------|
Bb[-----------------------------------------|
Gb[-----------------------------------------|
Db[-xx-4-----------------xx-4---------------|
Ab[-xx-2-----------------xx-2---------------|
Eb[-----------------------------------------|

Intro, Bkgrnd. (x4)
eb[-------5--2--5--2--5--2------------------|
Bb[-----------------------------------------|
Gb[-----------------------------------------|
Db[-----------------------------------------|
Ab[-2---------------------------------------|
Eb[-----------------------------------------|

Verse, Both (x2, Zakk w/ clean tone, let chords ring)
eb[-2------------0------------0------------2----|
Bb[-2------------2------------0------------2----|
Gb[-4------------2------------1------------4----|
Db[-4------------2------------2------------4----|
Ab[-2------------0------------2------------2----|
Eb[---------------------------0-----------------|

Chorus  (Note: You can barely hear the acoustic guitar, but he plays the exact same 
as Zakk.  Anyways, play this x2 w/ distortion.  Oh, yeah, let the chords ring)
eb[------------------------------------]------------------------------|
Bb[------------------------------------]------------------------------|
Gb[------------------------------------]------------------------------|
Db[-2-------------------------4--------]---------------------------4--|
Ab[-0------------2------------2--------]-4------------2------------2--|
Eb[--------------0---------------------]-2------------0---------------|
                                                ^^^^^^^^^^^^^^^^^^
                                         Play this once to end the Chorus

Intro pt. 1

Verse

Chorus

Intro pt. 2 (x2 this time)

GUITAR SOLO (Zakk, distortion w/ wah pedal)  As I said before, I'm not 100% sure here, 
on the really fast part, but it sounds okay with the wah pedal.
eb[--------------------------------------------------------------|
Bb[--------------------------------------16~~~~~~-16b17-14~~~~~--|
Gb[------------------------14-11-14-11---------------------------|
Db[------------14-12-14-12---------------------------------------|
Ab[-14-12-14-12--------------------------------------------------|
Eb[--------------------------------------------------------------|

eb[--------------------------------------------------------------------|
Bb[-14b16r14-12~~~~~~~~-12---------------------------------------------|
Gb[------------------------14-14--14b16-14b16-11-11-14-11-11-11-14-11--|
Db[--------------------------------------------------------------------|
Ab[--------------------------------------------------------------------|
Eb[--------------------------------------------------------------------|

eb[-----------------------------------------------------------------|
Bb[-----------------------------------------------------------------|
Gb[-11----11----11-11-11-13-11-13-11-13-14p13-11-13h14-14p11--------|
Db[----14----14-----------------------------------------------------|
Ab[-----------------------------------------------------------------|
Eb[-----------------------------------------------------------------|

eb[--------------------------------------------------------------|
Bb[--------------------------------------------------------------|
Gb[-11-11-11-13-11-13-14p13p11-11-11-11-14-13-14-13-14-11~~~~~~--|
Db[--------------------------------------------------------------|
Ab[--------------------------------------------------------------|
Eb[--------------------------------------------------------------|

eb[-------------------------------------------------19~~~~~~--|
Bb[-16~~~~~~-16b17-14~~~~~-14b16r14-12~~~~~~~~----------------|
Gb[-----------------------------------------------------------|
Db[-----------------------------------------------------------|
Ab[-----------------------------------------------------------|
Eb[-----------------------------------------------------------|

eb[-----------------------------------------------------------|
Bb[-----------------------------------------------------------|
Gb[-------------------------14-11-14-11-14b16~~~~-------------|
Db[-------------14-12-14-12-----------------------------------|
Ab[-14-12-14-12-----------------------------------------------|
Eb[-----------------------------------------------------------|

Chorus

Intro pt. 2 (x2)

And that's it.

Song Structure
Intro pt. 1
Intro pt. 2
Verse
Chorus
Intro pt. 2
Verse
Chorus
Intro pt. 2
GUITAR SOLO
Chorus
Intro pt. 2

Enjoy.  Sorry about the solo if it's wrong.  Other than that, I'm pretty sure the whole 
is 100% accurate.