I found a way to play this with only drop tuning your "E" string.  
The tuning results as follows: low to high (CADGBE)

Intro and Chorus
E|------------------------------------|
B|------------------------------------|
G|------------------------------------|
D|------------------------------------|
A|----------------8---8---8---8p5--8p5|
C|-0--0--0-0-0--3---3---3-------------|

Verse
E-------------------------------------|
B-------------------------------------|
G-------------------------------------|
D-------------------------------------|
A-----10------8-----8p5-8p5-8p5-------|
C--0-------0--------------------------|
^ Repeat a couple of times^ then play this
E----------------------------------------------|
B-----13---15-15-15-15-15-15-15-15-16-16-16-16-|
G---12-----------------------------------------|
D-10-------------------------------------------|
A----------------------------------------------|
C----------------------------------------------|

End verse on this

E--------------------------------|
B-----13-------------------------|
G---12---3-3-3-3-3-3-3-3-3-3-3-3-|
D-10-----------------------------|
A--------------------------------|
C--------------------------------|

and I don't know the solo